On the Biological Importance of the 3-hydroxyanthranilic Acid: Anthranilic Acid Ratio
نویسندگان
چکیده
منابع مشابه
On the Biological Importance of the 3-hydroxyanthranilic Acid: Anthranilic Acid Ratio
Of the major components of the kynurenine pathway for the oxidative metabolism of tryptophan, most attention has focussed on the N-methyl-D-aspartate (NMDA) receptor agonist quinolinic acid, and the glutamate receptor blocker kynurenic acid. However, there is increasing evidence that the redox-active compound 3-hydroxyanthranilic acid may also have potent actions on cell function in the nervous...
متن کامل3-hydroxyanthranilic Acid Metabolism
The participation of 3-hydroxyanthranilic acid as an intermediate in the biosynthesis of nicotinic acid from tryptophan was first demonstrated in certain mutant strains of Neurospora in 1948 by Bonner (1) and by Mitchell and Nyc (2). In addition, Mitchell et al. (3) found that 3-hydroxyanthranilic acid can replace nicotinic acid in the nutrition of the rat. In 1946 Singal et al. (4) noted a sub...
متن کاملhistological evaluation of the effect of three medicaments; trichloracetic acid, formocresol and mineral trioxide aggregate on pulpotomized teeth of dogs
چکیده ندارد.
15 صفحه اولEffect of 3-hydroxyanthranilic acid on the mitochondrial respiratory system.
Studies on the metabolites of tryptophan in urine, in various neoplastic diseases, have shown an unusual excretion pattern, some of these compounds being eliminated in greater amounts than in normal human beings (Boyland & Williams, 1956a, b; Musajo, Benassi & Parpajola, 1955; Quagliariello, Tancredi, Fedele & Saccone, 1961; Tompsett, 1959; Ivanova & Ramonova-Tskhovrebova, 1960; Price & Brown, ...
متن کاملStudies on purified 3-hydroxyanthranilic acid oxidase.
3-Hydroxyanthranilic acid oxidase is known to cat,alyze the oxidation of 3-hydroxyanthranilic acid to a very unstable aliphatic compound, which may either be spontaneously transformed into quinolinic acid or undergo enzymic conversion to picolinic or nicotinic acid, or both (l-3). According to Mason (4), this enzyme has been classified as an “oxygen transferase,” since the oxygen consumed, 1 mo...
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ژورنال
عنوان ژورنال: International Journal of Tryptophan Research
سال: 2010
ISSN: 1178-6469,1178-6469
DOI: 10.4137/ijtr.s4282